Genetic hypotheses for schizophrenia
نویسندگان
چکیده
منابع مشابه
Genetic hypotheses for schizophrenia
In their ‘common disease – rare alleles’ hypothesis McClellan et al (2007) come close to formulating an untestable theory. Although they refer to currently fashionable ‘candidate genes’ – e.g. dysbindin, neuregulin and DISC1 – it appears that they do not regard these as established. I agree that there is no consistency in the findings across even the largest genome scans conducted to date (samp...
متن کاملDevelopments in antipsychotic therapy with regard to hypotheses for schizophrenia
The typical antipsychotic drugs like chlorpromazine and haloperidol were discovered by serendipity in the 1950s. A number of so-called "me too" drugs with similar chemical structures and modes of action were marketed in the subsequent years. The first atypical antipsychotic, clozapine, was an exception because it lacked some of the pharmacological properties of the typical antipsychotics relate...
متن کاملFoetal origins of schizophrenia: testable hypotheses of genetic and environmental influences.
References http://bjp.rcpsych.org/content/184/5/383#BIBL This article cites 0 articles, 0 of which you can access for free at: permissions Reprints/ [email protected] write to To obtain reprints or permission to reproduce material from this paper, please to this article at You can respond http://bjp.rcpsych.org/cgi/eletter-submit/184/5/383 from Downloaded The Royal College of Psychiatri...
متن کاملThe Genetic Basis for Schizophrenia
When one talks about the genetics of schizophrenia, one can encounter a number of presuppositions in the audience. Many psychiatrists, psychologists, and sociologists today are skeptical whether genetic factors need to be considered at all. Lidz and his colleagues (1965), for example, believe that the existence of a genetic predisposition rests upon preconception and tradition, while evidence p...
متن کاملFeature selection using genetic algorithm for classification of schizophrenia using fMRI data
In this paper we propose a new method for classification of subjects into schizophrenia and control groups using functional magnetic resonance imaging (fMRI) data. In the preprocessing step, the number of fMRI time points is reduced using principal component analysis (PCA). Then, independent component analysis (ICA) is used for further data analysis. It estimates independent components (ICs) of...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: British Journal of Psychiatry
سال: 2007
ISSN: 0007-1250,1472-1465
DOI: 10.1192/bjp.191.2.180